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Abstract #3273

MR Technical Developments for Clinical Hyperpolarized 13C-Pyruvate Studies in Prostate Cancer Patients

Peder E. Z. Larson1, James Tropp2, Albert P. Chen3, Paul Calderon2, Simon Hu1, Galen Reed1, Sarah J. Nelson1, John Kurhanewicz1, Ralph Hurd2, Daniel B. Vigneron1

1Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, United States; 2Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; 3Applied Science Laboratory, GE Healthcare, Toronto, Ontario, Canada

We have developed and tested custom hardware and methods for future prostate cancer patient studies with hyperpolarized 13C-pyruvate, including 13C coils for prostate imaging, clean room dissolution DNP system, and hyperpolarized 13C pulse sequences.