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Abstract #3276

Improved Temporal Resolution for Hyperpolarized 13C 3D Dynamic MRSI with Compressed Sensing

Peder E. Z. Larson1, Simon Hu1, Michael Lustig2, Adam B. Kerr2, Sarah J. Nelson1, John Kurhanewicz1, John M. Pauly2, Daniel B. Vigneron1

1Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, United States; 2Electrical Engineering, Stanford University, Stanford, CA, United States

In this project, we developed improved sampling and reconstruction strategies to provide finer temporal resolution for hyperpolarized carbon-13 3D time-resolved MRSI with compressed sensing and multiband excitation pulses. These improved compressed sensing strategies better exploit the temporal redundancy. Results are shown with a 32-fold acceleration for a 2 sec temporal resolution, 3D dynamic MRSI acquisition.