Jae-Seung Lee1,2, Ravinder Regatte2, Alexej Jerschow3
1New York University, New York, NY, United States; 2Department of Radiology, New York University School of Medicine, New York, United States; 3Chemistry Department, New York University, New York, United States
The sodium ions bound to tissues and organs can provide us with an invaluable information on the onset of disorder, such as osteoarthristis and degenerative disc diseases, through their concentration and quadrupolar interaction/relaxation. Slow motion of sodium ions may occur in cells, and its altered relaxation properties further provide important insights into cell viability, such as in the case of tumor tissue, or in the monitoring of muscle activity. In this paper, we are presenting two 23Na MRI contrast schemes, one selecting sodium ions with quadrupolar interation and the other with quadrupolar relaxation.