Abstract #3420

A Simple Approach for Mapping CSF Volume Fraction

Qin Qin¹, Peter C.M. van Zijl¹

¹Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States

CSFs redistribution in response to local blood volume change during activation renders CSF volume fraction in baseline an important factor in fMRI models. Here a simple method of measuring CSF volume maps is proposed, which is based on the fitting of exponential decay of only CSF signal using a non-selective T2 preparation scheme. CSF volume fractions in ventricles were found to be about 1.0, while cortical volumes ranged from 0.05-0.5. The T2 of CSF was found to be 1654ms389ms.