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Abstract #3560

Interventricular Synchrony in Chronic Thrombo-Embolic Pulmonary Hypertension Recovers After Endarterectomy

Gert Jan Mauritz1, J. Tim Marcus1, Jochem Bosboom1, Anton Vonk Noordegraaf1

1VU University Medical Center, Amsterdam, Netherlands

The aim of this study is to assess whether the Left-Right (L-R) mechanical synchrony in Chronic Thrombo-Embolic Pulmonary Hypertension recovers after pulmonary endarterectomy. Nine patients were included, and underwent MRI myocardial tagging at baseline before, and 1 year after endarterectomy. The L-R delay in peak myocardial circumferential shortening decreased from 95 61 ms at baseline, to 2 47 ms after endarterectomy (p < 0.05). Cardiac output increased from 3.7 0.9 lit/min, to 4.8 0.6 lit/min (p<0.01). The L-R resynchronization and functional RV recovery are in line with reverse RV remodeling after endarterectomy.