Hassan Bagher-Ebadian1,2, Ramesh Paudyal1, Rajan Jain3, Jayant Narang3, James Russle Ewing1,2
1Neurology, Henry Ford Hospital, Detroit, MI, United States; 2Physics, Oakland University, Rochester, MI, United States; 3Radiology, Henry Ford Hospital, Detroit, MI, United States
In spoiled gradient echo sequences, the T1-weighting of image contrast is strongly affected by a nonlinear interaction of two sequence parameters, repetition time (TR) and flip angle () . Since the T1 is filed dependant, optimal set of is chosen to produce a field-dependent contrast behavior in MR imaging. Therefore, a pulse sequence with an optimal set of flip angle which provides a best Signal-to-Noise ratio would be useful in various quantitative methods. In the proposed study, a set of optimal flip angles which yield a better tissue contrast at different magnetic field strengths (3T, 7T) is determined.