Abstract #4323

High Resolution Magnetic Susceptibility Mapping in Patients with Clinically Isolated Syndrome

Ali Al-Radaideh¹, Samuel Wharton¹, Su-Yin Lim², Christopher Tench², Cris Constantinescu², Richard Bowtell¹, Penny Gowland¹

¹Sir Peter Mansfield MR Centre, The University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; ²Clinical Neurology, The University of Nottingham, Nottingham, Nottinghamshire, United Kingdom

Neurodegeneration in MS might be expected to cause an accumulation of iron in deep grey matter (dGM) structures. The aim of this study is to measure the susceptibility of dGm structures in patients with Clinically Isolated Syndrome (CIS), an early manifestation of MS.