Songtao Liu1, Roman Fleysher2,
Lazar Fleysher2, Chan-Gyu Joo3, Eva-Maria Ratai3,
R Gilberto Gonzalez3, Oded Gonen2
1National Institutes of Health Clinical
Center, Bethesda, MD, United States; 2New York University Medical
Center, New York, NY, United States; 3Massachusetts General
Hospital, Boston, MA, United States
The
rhesus macaque brain is an advanced model system for the study of
neurological diseases. To correct for unknown T1 weighting in MRS
quantification, the B1 corrected T1s of NAA, Cho and Cr in gray and white
matter structures of rhesus macaques were measured at 3T. Data was acquired
with 3D multivoxel proton MRSI at 180uL resolution. The macaques NAA, Cr and
Cho T1s are, 1232, 1238 and 1107ms. These values are in agreement with human
3T in vivo results.
Keywords