Iosif Alexandru Mendichovszky1, Constantina Chrysochou2, David L. Buckley3, Alan Jackson1, Phil A. Kalra2
1Wolfson Molecular Imaging Centre, The University of Manchester, Manchester, United Kingdom; 2Renal Department, Salford Royal Hospital, Salford, United Kingdom; 3University of Leeds, Leeds, United Kingdom
Atheromatous renovascular disease is a commonly encountered yet challenging disease to manage. The aim of the current study was to investigate renal parenchymal BOLD response to renal artery revascularization in patients with severe renal artery stenosis and correlate imaging findings with changes in SK-GFR (as measured by radioisotope techniques). No significant differences were found regarding baseline SK-GFR between kidneys that improved, remained stable, deteriorated or controls. R2* values were significantly higher in kidneys whose renal function subsequently improved vs. those who stayed stable, deteriorated or controls. In addition, the ratio of R2* to SK-GFR was significantly greater in improver kidneys.