Iosif Alexandru Mendichovszky1, Constantina
Chrysochou2, David L. Buckley3, Alan Jackson1,
Phil A. Kalra2
1Wolfson Molecular Imaging Centre, The
University of Manchester, Manchester, United Kingdom; 2Renal
Department, Salford Royal Hospital, Salford, United Kingdom; 3University
of Leeds, Leeds, United Kingdom
Atheromatous
renovascular disease is a commonly encountered yet challenging disease to
manage. The aim of the current study was to investigate renal parenchymal
BOLD response to renal artery revascularization in patients with severe renal
artery stenosis and correlate imaging findings with changes in SK-GFR (as
measured by radioisotope techniques). No significant differences were found
regarding baseline SK-GFR between kidneys that improved, remained stable,
deteriorated or controls. R2* values were significantly higher in kidneys
whose renal function subsequently improved vs. those who stayed stable,
deteriorated or controls. In addition, the ratio of R2* to SK-GFR was
significantly greater in improver kidneys.