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Abstract #4696

Mortality and Frequency of Nephrogenic Systemic Fibrosis

Giles Roditi1, Tara Collidge2, Peter Thomson2, Jamie Traynor2, Patrick Mark3, Scott Morris2, Keith Simpson2

1Radiology, Glasgow Royal Infirmary, Glasgow, Scotland, United Kingdom; 2Nephrology, Glasgow Royal Infirmary, Glasgow, Scotland, United Kingdom; 3Nephrology, Western Infirmary Glasgow, Glasgow, Scotland, United Kingdom

Nephrogenic systemic fibrosis (NSF) mortality was compared to a matched renal replacement therapy (RRT) population. Records searched with NSF and GBCA exposure identified and onset of RRT with survival to death or census. 1826 patients with RRT, 1812 with outcome data. Total 17 cases of NSF. Survival for GBCA exposed and NSF cohort measured by RRT onset or post scan survival not significantly different between these groups. Frequency of NSF cases over years studied follows the number of CE-MRA scans performed suggesting GBCA exposure causally implicated in development of NSF