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Abstract #4697

A Retrospective Analysis of Nephrogenic Systemic Fibrosis in a Population Undergoing Renal Magnetic Resonance Angiography Stratified by EGFR

Giles Roditi1, Tara Collidge2, Peter Thomson2, Keith Simpson2, Scott Morris2, Brown Michaela2, Anirudh Rao2

1Radiology, Glasgow Royal Infirmary, Glasgow, Scotland, United Kingdom; 2Nephrology, Glasgow Royal Infirmary, Glasgow, Scotland, United Kingdom

NSF associates with the administration of gadolinium contrast in renal impairment. Of 481 patients who underwent renal CE-MRA 3 patients were identified as having NSF. 2 had AKI when imaged, third had deteriorating CKD (eGFR 16.1) and developed NSF three years later when on dialysis following further CE-MRA. All cases of gadodiamide-associated NSF from our unit (n=16) 13 were established on dialysis, 2 had AKI and one had eGFR of 8.3 ml/min. All patients developing NSF have AKI or stage 5 CKD, we found no NSF cases with an eGFR >15 ml/min.