Renal Cell Carcinoma: 3.0-T Diffusion-Weighted MR Imaging for Subtypes Differentiation

Haiyi Wang¹, Aitao Guo², Dianjun Wang², Yuangui Gao¹, Xu Zhang³, Huiyi Ye¹

Renal cell carcinoma (RCC) is the most common malignant renal tumor in adults, with the three major subtypes, clear cell RCC, papillary RCC, and chromophobe RCC. Because of clincal needs for RCC subtypes differentiation, this study explores the ADC values of pathologically-proved clear cell, papillary, and chromophobe RCC subtypes, and the conclusion is drawn that they possess different diffusion characteristics that can be distinguished using DWI on the basis of the ADC, with high sensitivity and specificity, potentially improving the accuracy of pretreatment diagnosis and selection of clinical therapy.