Sophie F. Riches1, Veronica A. Morgan2, Sharon Giles2, Catherine Simpkin2, Nandita deSouza1
1Cancer Research UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; 2Cancer Research UK and EPSRC Cancer Imaging Centre, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
Tumor detection within the prostate depends on T2-weighted contrast. This study compares T2 values at 3T and 1.5T and investigates differences in T2 contrast with fractional volume of the peripheral zone (PZ). T2 values obtained at 3T were not significantly different to those at 1.5T for any prostate region. Patients with a low PZ to whole prostate volume showed significantly reduced T2 in PZ compared to those with larger PZ fractions. In patients with low fractional PZ volume, therefore, T2 values of PZ may be indistinguishable from tumor, reducing the ability to detect tumor within the PZ in these patients.