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Abstract #4780

Relative Conspicuity of Prostate Cancer: Apparent Diffusion Coefficient Versus Dynamic Contrast Enhancement

Daniel Jason Aaron Margolis1, Timothy McClure1, Steven Raman1

1Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States

Diffusion-weighted imaging (DWI) and dynamic contrast enhancement (DCE) can localize prostate cancer in situ, but it is unclear if one is superior. DWI, Ktrans, Kep, Ve, and T2WI are compared with surgical pathology in 23 patients using a unitless variable, the conspicuity ratio, the difference of the values from the ROI of the lesion and the contralateral side, divided by the average of these values. Prostate cancer is more conspicuous on DWI ADC maps and on DCE than on T2WI, and more conspicuous on DCE than on ADC, but Ktrans and Kep are not significantly different in terms of conspicuity.