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Abstract #4822

Using MRI to Monitor Tumorigenesis in a Murine Model of Melanoma Brain Metastasis

Amr Morsi1,2, Evelyn Voura1,2, Susan Pun2, Minh Dung Hoang2, Asad Baig3, Erik Parker1, John Golfinos1, Youssef Zaim Wadghiri2

1Neurosurgery, NYU langone medical center, NYC, NY, United States; 2RADIOLOGY, NYU langone medical center, NYC, NY, United States; 3Radiology, NYU langone medical center, NYC, NY, United States


Our group at NYU medical center tried to establish a murine model of melanoma brain metastasis and implement an MRI protocol to longitudinally follow the metastatic tumor over time which will aid in therapeutic studies. Although the established model spread to unconventional sites ( intra-ventricular and meningeal) instead of parenchymal, the MRI studies conducted showed promising results since it echoed the MRI characteristic findings observe in clinical settings.