Magnetic Microparticle Size Optimization for Susceptibility Contrast Imaging

Nina Olamaei¹, Frederick Gosselin, Farida Cheriet, Sylvain Martel

The effective intravoxel dephasing makes the magnetic microparticles promising candidate for MR imaging. In the present work, the behavior of the susceptibility artifact is investigated as microparticles are broken to smaller particles using a numerical simulation. The diameters of the particles were varied while keeping the total volume of magnetic materials constant. The signal loss was calculated for different combinations of particle sizes and TEs. The results suggest that the distribution of smaller particles over a surface creates a more pronounced signal loss compared to that created by larger particles on an identical total volume.