Prodromos Parasoglou1,2, Cesar a
Berrios-Otero2,3, Brian J. Nieman4, Daniel H. Turnbul2,3
1Skirball Institute of
Biomolecular Medicine, New York University School of Medicine , New York,
United States; 2Department of Radiology, New York University
School of Medicine, New York, United States; 3Skirball Institute
of Biomolecular Medicine, New York University School of Medicine, New York,
United States; 4Mouse Imaging Centre, The Hospital for Sick
Children, Toronto, Ontario, Canada
In this work we report the acquisition of high-resolution 3D images of the vasculature of embryos starting at embryonic day E10.5, without the use of a contrast agent. Mouse embryos were imaged in-utero between E10.5 and E17.5. To our knowledge this is the first time high resolution 3D images have been acquired at this early stage, showing the exciting possibility of performing longitudinal studies of embryonic development at stages close to the onset of neurogenesis and embryonic cardiac activity.