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Abstract #2441

Temporal Evolution of the Irradiated Parotid Glands: Volume & ADC Value

Chun-Jung Juan1, Cheng-Chieh Cheng2, Hsiao-Wen Chung1,2, Yee-Min Jen3, Hing-Chiu Chang2,4, Su-Chin Chiu2, Cheng-Yu Chen1, Chun-Jen Hsueh1, Yaoh-Shiang Lin5, Guo-Shu Huang1

1Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan; 2Graduate Institute of Biomedical Electronics & Bioinformatics, National Taiwan University, Taipei, Taiwan; 3Department of Radiation Oncology, Tri-Service General Hospital, Taipei, Taiwan; 4Applied Science Laboratory, GE Healthcare, Taipei, Taiwan; 5Department of Otorhinolaryngology-Head & Neck Surgery, Tri-Service General Hospital, Taipei, Taiwan

Functional impairment and volume reduction were frequently encountered in nasopharyngeal carcinoma patients who are treated with radiation therapy. In this preliminary study, the temporal evolutions of structural and physiological features of the irradiated parotid glands were investigated with dynamic contrast-enhanced MRI and diffusion-weighted MRI.