Abstract #2441

Temporal Evolution of the Irradiated Parotid Glands: Volume & ADC Value

Chun-Jung Juan¹, Cheng-Chieh Cheng², Hsiao-Wen Chung^1,2, Yee-Min Jen³, Hing-Chiu Chang^2,4, Su-Chin Chiu², Cheng-Yu Chen¹, Chun-Jen Hsueh¹, Yaoh-Shiang Lin⁵, Guo-Shu Huang¹

¹Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan; ²Graduate Institute of Biomedical Electronics & Bioinformatics, National Taiwan University, Taipei, Taiwan; ³Department of Radiation Oncology, Tri-Service General Hospital, Taipei, Taiwan; ⁴Applied Science Laboratory, GE Healthcare, Taipei, Taiwan; ⁵Department of Otorhinolaryngology-Head & Neck Surgery, Tri-Service General Hospital, Taipei, Taiwan

Functional impairment and volume reduction were frequently encountered in nasopharyngeal carcinoma patients who are treated with radiation therapy. In this preliminary study, the temporal evolutions of structural and physiological features of the irradiated parotid glands were investigated with dynamic contrast-enhanced MRI and diffusion-weighted MRI.