Abstract #2518

Abnormal Resting State Functional Connectivity as a Marker for Diagnosing & Predicting Recovery in Mild Traumatic Brain Injury

Guangyu Chen¹, Thomas Hammeke², Gang Chen¹, Michael McCrea², Barney Douglas Ward¹, Sarah Miller³, Shi-Jiang Li¹,⁴

¹Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; ²Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, United States; ³St. Mary's Regional Medical Center, St. Mary's Regional Medical Center, Enid, OK, United States; ⁴Psychiatry & Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI, United States

Mild traumatic brain (mTBI) injury shows significant functional connectivity changing between several cortex regions including hippocampus, middle frontal gyrus, superior frontal gyrus et al, and several cerebellar regions. These functional connections also can be used to monitor the recovery processing in seven weeks. Some of these connections have significant correlation with memory and balance performance scores.