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Abstract #3073

Initial Clinical Testing of RESOLVE: High-Resolution Diffusion Weighted Imaging at 3T

Dorota Jakubowski Wisner1, Vibhas S. Deshpande2, Bonnie N. Joe1, David A. Porter3, C. Belinda Chang1, Gerhard A. Laub2, Nola Hylton1

1Radiology & Biomedical Imaging, Univeristy of California, San Francisco, San Francisco, CA, United States; 2MR Research & Development, Siemens Medical Solutions USA, Inc., San Francisco, CA, United States; 3MR Research & Development, Siemens Medical Solutions, Erlangen, Bavaria, Germany

Diffusion weighted imaging (DWI) has shown promise for improving the specificity of breast MRI, but is hampered by poor resolution, field homogeneity, and overall image quality at 3T. We compare a novel DWI technique named RESOLVE against standard single short spin echo EPI for lesion conspicuity and level of detail in 15 patients, and for ADC values compared to pathology in a smaller sub-selection of these patients. Preliminary results suggest that RESOLVE provides robust, high-resolution DWI at 3T, which may eventually advance the potential clinical utility of DWI in breast imaging.