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Abstract #3110

Assessing the Tumour Microenvironment with DCE-MRI & DCE-Ultrasound

Firas Moosvi1,2, Peter Bevan3, Colleen Bailey1,2, Greg Stanisz1,2

1Imaging Physics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 2Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 3McMaster University, Hamilton, Ontario, Canada

Non-invasive imaging modalities such as MRI and ultrasound (US) are perfectly suited for a dual-modality imaging protocol. Both MRI and US possess unique advantages and the potential applications of these techniques span the entire spectrum of disease. The first hurdle of developing this protocol is the difficulty in ensuring parameters from the same image region are compared. The second issue is the lack of physiological meaning in parameter comparisons across imaging modalities. In this talk, we present potential solutions to both these problems and explore the feasibility of using a dual-modality imaging protocol to assess the tumour microenvironment.