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Abstract #4283

High Resolution Distortion-Free Diffusion-Tensor Imaging of Craniovertebral Junction

Mami Iima1, Akira Yamamoto1, Tomohisa Okada1, Mitsunori Kanagaki1, Denis Le Bihan2,3, Seiko Kasahara1, Emiko Morimoto1, Satoshi Nakajima1, Ryo Sakamoto1, Taha Mohamed Mehemed1, Kaori Togashi1

1Department of Diagnostic Imaging & Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan; 2Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan; 3Neurospin, CEA-Saclay Center, Gif-sur-Yvette, France

We implemented GRAPPA-accelerated RS-EPI DTI and SS-EPI DTI at 3T MR scanner with 32-channel head coil, and evaluated the feasibility of clinical application by comparing these two acquisition methods. RS-EPI has much reduced susceptibility compared with SS-EPI and can be a potential to be an alternative to SS-EPI DTI for evaluating CVJ lesion, such as demyelinating disease, neurodegenerative disease, brain tumors, skull base tumor, and inflammation.