Charng-Chyi Shieh1,2, Yu-Chun Lin1,2, Jiun-Jie Wang2,3, Yau-Yau Wai1,2, Chun-Huang Hsieh1, Sheng-Chieh Chan3,4, Tzu-Chen Yen3,4, Shu-Hang Ng1,2
1Medical Imaging & Intervention, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan; 2Medical Imaging & Radiological Science, Chang Gung University, Taoyuan, Taiwan; 3Molecular Imaging Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan; 4Nuclear Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan
We prospectively compared the diagnostic capability of 3.0-Tesla whole-body (WB) MRI and FDG-PET-CT for bone metastasis in nasopharyngeal carcinoma (NPC). Twenty-four (6.2%) of our 388 NPC patients were diagnosed as having bone metastases. On a patient-based analysis, WB-MRI and FDG-PET-CT showed the similar sensitivity and specificity for bone metastasis (70.8 % vs 75.0 %, P=0.999; 99.5% vs 98.4%, P=0.289, respectively). Their diagnostic capabilities were equal (0.909 vs 0.909). We concluded that 3.0-Tesla WB-MRI is a feasible technique for the detection of bone metastasis in NPC patients, with similar sensitivity and equal diagnostic capacity to FDG-PET-CT.