Trevor Wade1,2, Charles McKenzie2,3, Brian Rutt4
1Robarts Research Institute, London, Ontario, Canada; 2Biomedical Engineering, the University of Western Ontario, London, Ontario, Canada; 3Medical Biophysics, the University of Western Ontario, London, Ontario, Canada; 4Department of Radiology, Stanford University, Stanford, CA, United States
A theoretical propagation of noise analysis was conducted on 3 flip angle (α) imaging techniques (the saturated double angle method, actual flip angle imaging, and the non-inverted double angle Look-Locker method). This analysis was used to predict the optimal imaging parameters, and the imaging efficiency (α to α noise ratio (ANR) normalized by scan time). The predicted ANR was then compared to the experimentally measured value for a range of flip angles and T1 values.