Abstract #0794

High Resolution Sodium MRI and Abnormal Sodium Ion Pump in the Bipolar Brain

Fernando Emilio Boada¹, Vincent Lee¹, Yongxian Qian¹, Mary Phillips², David Kupfer²

¹Radiology and Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States; ²Psychiatry, University of Pittsburgh, Pittsburgh, PA, United States

Regional Differences in Sodium Content between Euthymic Bipolar Subjects and Normal Controls were studied using High Resolution Sodium MRI at 7T. Results support the existence of statistically significant differences in sodium concentration in the basal ganglia but not in the average total brain concentration.