Abstract #0953

Manganese Concentration Mapping with Magnetic Resonance & Positron Emission Tomography

Geoffrey Topping¹, Andrew Yung², Paul Schaffer³, Piotr Kozlowski², Thomas Ruth³, Vesna Sossi¹

¹Physics and Astronomy, University of British Columbia, Vancouver, British Columbia, Canada; ²MRI Research Centre, University of British Columbia, Vancouver, British Columbia, Canada; ³Nuclear Medicine, TRIUMF, Vancouver, British Columbia, Canada

Manganese concentration was measured in the rat brain using MRI T1 mapping and positron emission tomography with the radiotracer Mn-52 after IP and IV injections. Within the brain, results are similar between modalities, with short-term Mn accumulation seen prominently in the pituitary. This similarity suggests pharmacological effects do not significantly affect short term Mn uptake.