Comparisons of Prostate Cancer Tissue Metabolic Intensities and Metabolomic Profiles from African American and Caucasian Patients

Emily Decelle¹, Phillip Knape², Chin-Lee Wu¹, W Scott McDougal¹, Leo L. Cheng¹

Prostate cancer exhibits a racial disparity such that African American men have a significantly higher incidence and mortality rate than Caucasian men. The possible ethological or biological factors responsible for these differences remain unknown but may reveal much about the disease that has become the most frequently diagnosed cancer in men. In this study, we compare tissue metabolic intensities and the metabolomic profiles of prostate cancer from African American patients with those from matched Caucasian patients in order to expose metabolic similarities and differences between the two patient populations.