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Abstract #1952

Comparison of EPIK and Parallel EPI in Dual-Shot DSC

Ke Zhang1, Seong Dae Yun1, Irene Neuner1, 2, Christian Filss1, Karl-Josef Langen1, Nadim Joh Shah1, 3

1Institute for Neuroscience and Medicine, Medical Imaging Physics (INM-4), Forschungszentrum Jlich, Jlich, Germany; 2Faculty of Medicine, Department of Psychiatry and Psychotherapy, JARA, RWTH Aachen University, Aachen, Germany; 3Faculty of Medicine, Department of Neurology, JARA, RWTH Aachen University, Aachen, Germany

For dynamic susceptibility contrast (DSC) based perfusion, parallel EPI (pEPI) has been the traditional method for readout. However, image artefacts such as distortions in the peripheral region are still problematic. EPIK which combines the keyhole imaging scheme with multishot EPI approaches has been presented to reduce the geometric distortion. In this work, we compare EPIK and pEPI with T2*-weighted images in a dual-shot contrast agent DSC study. Three representative human brain tumour cases demonstrate that the feasibility of DSC using EPIK. EPIK can offer less distortion in peripheral region, higher perfusion contrast in DSC, and same temporal resolution as pEPI.