The Measurement and Interpretation of Intravoxel Incoherent Motion (IVIM) of Skeletal Muscle in vivo: Preliminary Results

Yoshikazu Okamoto¹, Tomonori Isobe, Yuji Hirano²

The soleus muscle (SOL) and the flexor digitorum profundus muscle (FDP) was scanned to cover b-factors from 0 to 3,500 s/mm2 of diffusion weighted image. A statistical comparison between monoexponential and biexponential fits was performed, and a statistically improved fit (P < 0.05; F test) was observed in all cases. The fast and slow diffusion fractions and fast and slow apparent diffusion coefficient (ADCfast and ADCslow) were 0.92 } 0.05, 0.08 } 0.05, 1.68 } 0.14, and 0.26 } 0.17, for SOL, and 0.95 } 0.01, 0.05 } 0.01, 1.75 } 0.22, and 0.01 } 0.02, respectively, for FDP.