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Abstract #2390

Rapid Liver T1 Mapping with Two Image Acquisitions

Sohae Chung1, Elodie Breton2, Leon Axel1

1Center for Biomedical Imaging, Radiology Department, NYU Langone Medical Center, New York, NY, United States; 2LSIIT - AVR, University of Strasbourg - CNRS, Strasbourg, France

Most cirrhotic livers have qualitatively inhomogeneous hepatic texture in contrast-enhanced MR images; this is related to the degree of liver necrosis, inflammation, and fibrosis. Quantitative liver T1 mapping could potentially provide additional useful information on liver abnormalities. However, conventional T1 mapping approaches, using a multi-point inversion recovery imaging sequence, have long acquisition times (≥ 20s) and are sensitive to abdominal organ or respiratory motion; this can lead to T1 fitting errors. In this work, a single-point T1 mapping method was used to calculate the liver T1 map with just two images acquired in a short (2s) acquisition time.