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Abstract #2392

An Improved Three-Dimensional Look-Locker Sequence for T1 Measurements

Cheukkai Hui1, Ponnada Narayana2, Houston, TX, United States; 2Radiology, UT Health, Houston, TX, United States

A truly centric scheme along both phase encoding directions in the k-space for three-dimensional Look-Locker (LL) sequence for fast T1 acquisition is implemented. In addition, a multi-step fitting algorithm which utilizes a χ 2 weighted angle maps for improving the accuracy of T1 measurements is presented. The performance of this technique is evaluated both on a gel phantom and rodent brain. The proposed method can improve both the acquisition and analysis of T1 values.