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Abstract #3116

Detection of the Grey Matter Lesions in MTR and MPRAGE in 7T

Anna I. Blazejewska1, Olivier Mougin2, Rasha Abdel-Fahim3, Niraj Mistry3, Richard W. Bowtell2, Nikos Evangelou3, Penny A. Gowland2

1Sir Peter Mansfield Magnetic Resonance Centre , University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham; 3Neurology, Nottingham University Hospitals NHS Trust

Cortical lesions in multiple sclerosis are difficult to detect. This study compares lesions detection on high resolution MTR maps and MPRAGE images acquired at 7T. MTR was most sensitive to cortical lesions and MPRAGE was more sensitive to mixed lesions (lying on the grey/white matter boundary).