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Abstract #3501

A Cluster-Based Method for Parametric Maps in Dynamic Contrast-Enhanced -MRI

Patrik Brynolfsson1, Anders Garpebring1, Thomas Asklund2, Tufve Nyholm1

1Dept. of Radiation Sciences, Ume University, Ume, Sweden; 2Division of Oncology, Dept. of Radiation Sciences, Ume University, Ume, Sweden

An alternative method for generation of parametric maps in dynamic contrast-enhanced MRI was investigated on in vivo data. The method is based on clustering of voxels with similar contrast agent kinetics. In this study, the clustering method was compared with a conventional voxel-by-voxel analysis. The results showed that the calculation time was reduced by a factor 8 for a single slice, and parametric maps looked visually similar. However, a correlation analysis revealed that improvements are needed for the cluster-based analysis to reach its full potential.