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Abstract #3526

Quantification of Contrast Agent in Human Brain Using Quantitative Susceptibility Mapping

Tian Liu1, Yinghua Ma2, Min Lou3, Timothy Vartanian2, Yi Wang4

1MedImageMetric LLC, New York, NY, United States; 2Neuroscience and Neurology, Weill Cornell Medical College, New York, United States; 3Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hang Zhou, Zhe Jiang, China; 4Radiology, Weill Cornell Medical College, New York, United States

In Vivo quantification of contrast agent using T1/T2* based methods are subject to large errors due to quenching effects. On the other hand, superparamagnetic iron oxide or gadolinium based contrast agents are highly paramagnetic, making them ideal candidates for quantitative susceptibility mapping. In this study, we demonstrated the feasibility of using QSM for the investigation of vasculature in the human brain tumor.