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Abstract #3569

Measuring Cell Permeability with Diffusion-Weighted Simultaneous Spin-Echo and Stimulated Echo EPI

Sharon Peled1, Saadallah Ramadan2, Carl-Fredrik Westin1

1Radiology, Brigham and Women's Hospital, Boston, MA, United States; 2School of Health Sciences, University of Newcastle, Callaghan, NSW, Australia

A comparison of the spin echo and stimulated echo DWI signals may yield an in vivo biomarker reflecting the permeability and/or thickness of the myelin sheath. The spin echo and stimulated echo DW-EPI signals can both be measured after a single excitation.