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Abstract #4269

Whole Cerebrum Myelin Water Imaging in Less Than 15 Minutes

Thomas Prasloski1, Alexander Rauscher2, 3, Alex MacKay1, 2, Madeleine Hodgson1, Irene Vavasour2, Corree Laule4, Burkhard Mdler5

1Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada; 2Department of Radiology, University of British Columbia; 3UBC MRI Research Centre, University of British Columbia; 4Department of Pathology & Laboratory Medicine, University of British Columbia; 5Department of Neurosurgery, University of Bonn

We present the application of an accelerated GRASE pulse sequence in the acquisition of data used to generate myelin water fraction maps. This sequence allows whole cerebrum coverage in scan times of less than 15 minutes. Further, the results of region of interest analysis indicate that myelin water fraction values correlate well with those of a previously validated sequence. Fast myelin water imaging could present new opportunities in both clinical and scientific research.