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Abstract #4391

Reproducibility of Anterior Cingulate 1H MRS Data at 7T

S. Andrea Wijtenburg1, Laura M. Rowland1, Elena A. Spieker1, Richard A. E. Edden2, 3, Peter B. Barker2, 3

1Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, United States; 2Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, MD, United States; 3F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

In this study, 7T spectroscopic data were acquired from healthy volunteers on two separate visits to determine the reproducibility of a short TE STEAM localization sequence. Voxels were placed in the anterior cingulate cortex, and all data were quantified using LCModel. Mean absolute differences were below 10% for most metabolites including GABA, suggesting that complex spectral editing techniques may not be necessary at higher field strengths.