Andrew B. Rosenkrantz1, Nicole Hindman1, Hersh Chandarana1, Fang-ming Deng2, James S. Babb1, Samir S. Taneja3, Christian Geppert4
1Radiology, NYU Langone Medical Center, New York, United States; 2Pathology, NYU Langone Medical Center, New York, United States; 3Urologic Oncology, NYU Langone Medical Center, New York, United States; 4Siemens Medical Systems, New York, United States
49 prostate cancer patients underwent 3T MRI including DWI with b-values 50 and 1000 mm2/sec. Computed DW-images with b-value 1500 were generated from the lower b-value images without additional scan time. Directly acquired b1500 images were also obtained in 39 patients. For two independent readers, using prostatectomy as reference, computed b-1,500 images had higher sensitivity and PPV for tumor than direct b-1,000 images and no significant difference than direct b-1,500 images. Scores for diagnostic confidence, tumor conspicuity, distortion, and benign prostate tissue suppression, were also significantly better for computed b-1,500 images than for direct b-1,000 images for both readers.