Meeting Banner
Abstract #0719

Initial Clinical Application of Simultaneous MR Angiography and Perfusion (MRAP) in Peripheral Arterial Disease

Katherine L. Wright1, Arash Aghel2, Nicole Seiberlich1, Mark A. Griswold, 13, Anne Hamik2, Vikas Gulani, 14

1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 2Case Cardiovascular Research Institute, Case Western Reserve Univ. and University Hospitals, Cleveland, OH, United States; 3Radiology, University Hospitals Case Medical Center, Cleveland, OH, United States; 4Radiology, Case Western Reserve University, Cleveland, OH, United States

Complete evaluation of both large and small vessels would typically require two separate contrast enhanced acquisitions: MR angiography and dynamic contrast enhanced (DCE) MRI. MRAP (MR Angiography and Perfusion) is a technique that allows for simultaneous acquisition of both these exams by using an optimized, 3D, time-resolved contrast-enhanced acquisition with high spatial/temporal resolution. This preliminary study applies MRAP to the clinical evaluation of peripheral arterial disease (PAD). DCE-MRI perfusion measurements from various muscles in the leg were correlated to ankle brachial index (ABI) data to evaluate the use of MRAP in PAD.