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Abstract #1266

Improving Visualization of Mouse Brain Nuclei in Manganese-Enhanced MRI Using Super-Resolution Reconstruction

Esben Plenge1, Dana S. Poole2, Dirk H.J. Poot3, Egbert A.J.F. Lakke4, Wiro J. Niessen3, 5, Erik Meijering3, Louise van der Weerd2, 6

1The Biomedical Imaging Group (BIGR), Radiology & Medical Informatics, Erasmus MC University Medical Center, Rotterdam , Netherlands; 2Radiology, Leiden University Medical Center,, Leiden, Netherlands; 3The Biomedical Imaging Group (BIGR), Radiology & Medical Informatics, Erasmus MC University Medical Center, Rotterdam, Netherlands; 4Anatomy, Leiden University Medical Center, Leiden, Netherlands; 5Quantitative Imaging Group, Dept. of Imaging Science and Technology, Faculty of Applied Sciences, Delft University of Technology, Delft, Netherlands; 6Human Genetics, Leiden University Medical Center, Leiden, Netherlands


In this study we demonstrate how super-resolution reconstruction (SRR) can be used to overcome the anisotropy issue and produce high-resolution isotropic volumes in acquisition times compatible with in-vivo experiments.