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Abstract #1709

MR Microscopy of ECM Alterations in a Mouse Model of Pancreatic Cancer

Palamadai N. Venkatasubramanian1, George Iordanescu1, Paul J. Grippo2, Richard Knop1, Alice M. Wyrwicz1

1Center for Basic M.R. Research, NorthShore University HealthSystem, Evanston, IL, United States; 2Robert H Lurie Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, United States

Although pancreatic ductal adenocarcinoma is associated with marked stromal changes, MR imaging has not been used to characterize those changes. We have examined and quantified pancreatic cancer-associated stromal changes in a mouse model using 3D MR microscopy.