in vivo Localized Correlated Spectroscopy Using Spectral Spatial Coherence Transfers

Galen D. Reed¹, Trey Jalbert¹, Gerd Melkus¹, Simon Hu¹, Peder E.Z. Larson¹, Sarah J. Nelson¹, John Kurhanewicz¹, Daniel B. Vigneron¹

A localized correlated spectroscopy sequence using spectral spatial coeherence transfer / water suppression pulses is presented. High bandwidth and low peak power was achieved by phase modulation of the spectral filter and using phase-matched refocusing pulses. Insensitivity to transmitter power offsets is demonstrated in phantoms and compared to correlated spectroscopy acquired using selective presaturation. Preliminary data from vounteers indicate robust water suppression without cross peak degredation due to water contamination.