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Abstract #2548

MTRRex a New Spillover and MT Correction Method for Quantitative Pulsed Steady-State CEST

Moritz Zaiss1, Steffen Goerke1, Peter Bachert1

1Dept. of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, BW, Germany

CEST evaluation suffers from concomitant effects as direct water saturation (spillover) and MT. We present a new spillover correction for pulsed CEST which yields the exchange dependent relaxation in the rotating frame Rex. We proof our method at creatine model solutions and show additionally, that also quantification is possible and therefore calculation of pH and creatine concentration maps.