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Abstract #3492

Difussion Tensor Imaging Studies in Limb-Girdle Muscular Distrophies

Hidalgo-Tobon S. Silvia1, Gabriela R. Hernandez Salazar2, S Vargas-Caas2, O. Marrufo-Melendez3, S. Solis Najera4, Alfredo O. Rodriguez5, Rosa Delgado-Hernandez6

1Universidad Autonoma Metropolitana, Mexico City, Mexico, Mexico; 2Insituto Nacional de Neurologia, Mexico, Mexico; 3Insituto Nacional de Neurologia, DF, Mexico, Mexico; 4UNAM, MExico, Mexico; 5UAM, DF, Mexico, Mexico; 6Imagenologia, Instituto Nacional de Neurologia y Neurocirugia, DF, Mexico, Mexico

Limb-girdle muscular dystrophies (LGMD) are a group of autosomal dominantly or recessively inherited muscular dystrophies that also present with primary proximal (limb-girdle) muscle weakness. This type of dystrophy involves the shoulder and pelvic girdles, distinct phenotypic or clinical characteristics are recognized. LGM dystor-phies affect posterior thigh muscle compartment, predomi-nantly gracilis and sartorius muscles. In the thigh, muscles at the back are affected, with a tendency to preserve the tibi-alis anterior and gastrocnemius. In this study we analyze DTI images, relation between the number of tracts, FA, and lenght in sartorius and gracilis muscle.