Abstract #3950

Polarization Loss from Magnetic Field Noise

Shawn Wagner¹,², Jose Agraz³, Alexander Grunfeld⁴, Debiao Li¹,²

¹Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States; ²Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States; ³Bioengineering, UCLA, Los Angeles, CA, United States; ⁴Life Sciences, UCLA, Los Angeles, CA, United States

Hyperpolarization by RF irradiation spin transfer utilizing parahydrogen requires low magnetic fields. These fields have been created with solenoids using current to determine the field strength. This abstract is intended to show how noise in the current results in magnet field noise, leading to sporadic loss of polarization in echo sequences. The loss in temporal refocusing is a crucial issue in the reliability of RF irradiation spin transfer PHIP hyperpolarization, since the last part of such sequences contains an echo period in the transverse plane.