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Abstract #3954

Multi-Resonance 3D Spin-Echo EPI With Chemical Separation For Fast Hyperpolarized 13C MRI

Peter J. Shin1, Peder E.Z. Larson1, Martin Uecker2, Michael Lustig2, Daniel B. Vigneron1

1Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States; 2Electrical Engineering and Computer Science, UC Berkeley, Berkeley, CA, United States

In hyperpolarized 13C experiments, data acquisition window is limited by the rapid metabolism and T1 relaxation of the hyperpolarized signal. This necessitates fast imaging schemes such as echo planar imaging (EPI). In this project, we developed a fast 3D EPI sequence for rapid 13C data acquisition and an accompanying multi-channel chemical separation method based on joint estimation of coil sensitivities and images of different molecules.