Metabolite Proton T1 Relaxation Times in the Rat Brain in vivo at 17.2 Tesla

At ultra-high magnetic fields such as 17.2 T, it is crucial to establish T ₁ and T ₂ relaxation times in order to optimize MRS acquisition parameters and to achieve proper quantification. In this study we present measurements of T ₁ relaxation times of 20 metabolites and macromolecules in the rat brain in vivo at 17.2T. Results show a convergence of T ₁ relaxation times to 1690 ms, with the exception of Taurine (2212 99 ms) and Cr-CH2 (1152 32 ms). T ₁ values were slight longer than those measured at lower magnetic fields, which is consistent with the Bloembergen-Purcell-Pound theory of dipolar relaxation.

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