Abstract #0070
Metabolite Proton T1 Relaxation Times in the Rat Brain in vivo at 17.2 Tesla
Alfredo Liubomir Lopez Kolkovsky 1 , Boucif Djemai 1 , and Fawzi Boumezbeur 1
1
CEA/Saclay/Neurospin, Commissariat a
l'Energie Atomique, Gif-sur-yvette, Essonne, France
At ultra-high magnetic fields such as 17.2 T, it is
crucial to establish T
1
and
T
2
relaxation
times in order to optimize MRS acquisition parameters
and to achieve proper quantification. In this study we
present measurements of T
1
relaxation
times of 20 metabolites and macromolecules in the rat
brain
in
vivo
at
17.2T. Results show a convergence of T
1
relaxation
times to 1690 ms, with the exception of Taurine (2212
99 ms) and Cr-CH2 (1152 32 ms). T
1
values
were slight longer than those measured at lower magnetic
fields, which is consistent with the
Bloembergen-Purcell-Pound theory of dipolar relaxation.
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