Abstract #0100
A combined acquisition of T 1 and AxCaliber can link between axon diameter and myelination
Daniel Barazany 1,2 , Derek K Jones 2 , and Yaniv Assaf 1
1
Department of Neurobiology, Tel Aviv
University, Tel Aviv, Israel,
2
CUBRIC
School of Psychology, Cardiff University, Cardiff,
United Kingdom
AxCaliber is a diffusion MRI method that models the axon
diameter distribution. here we introduce a noval
acquisition that Combines T1 and AxCaliber to provide
further insight into white matter micro-structure as it
links between axons at different size and their T1. This
kind of combined acquisition and analysis allows to
estimate the effect of myelin content on T1 and its
relation to axon diameter. The results of this work
demonstrate that MRI allows to probe white matter tissue
micro-structure providing invaluable high details that
so far could be extracted only by invasive techniques.
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