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Abstract #0117

Literacy and the Arcuate Fasciculus

Michel Thiebaut de Schotten 1,2 , Laurent Cohen 1 , Eduardo Amemiya 3 , Lucia Braga 3 , and Stanislas Dehaene 4

1 Brain and Spine Institute, Paris, France, 2 Natbrainlab - Institute of Psychiatry, London, United Kingdom, 3 SARAH NetworkInternational Center for Neurosciences and Rehabilitation, Brasilia, Brazil, 4 Collge de France, Paris, France

The acquisition of literacy results from an effortful learning process that leads to functional changes in several cortical regions. We explored whether learning to read also leads to anatomical changes within the left intrahemispheric white matter pathways that interconnect these regions. We revealed that the acquisition of literacy is associated with a reinforcement of left temporo-parietal connections whose microstructure predicts overall reading performance and the functional specialization of the Visual Word Form Area. This anatomical magnetic resonance imaging marker may be useful to predict developmental reading disorders.

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