Abstract #0236
Electrical Characteristics of Chronic Iron-laden Myocardial Infarcts: Initial Study in Canine Hearts
Ivan Cokic 1 , Avinash Kali 2 , Xunzhang Wang 2 , Hsin-Jung Yang 2 , Richard L. Q. Tang 2 , Anees Thajudeen 2 , Michael Shehata 2 , Allen M. Amorn 2 , Enzhao Liu 2 , Brian Stewart 3 , Nathan Bennett 3 , Doron Harlev 3 , Sotirios A. Tsaftaris 4 , Warren M. Jackman 5 , Sumeet S. Chugh 2 , and Rohan Dharmakumar 2
1
Cedars-Sinai Medical Center, Los Angeles,
CA, United States,
2
Cedars-Sinai
Medical Center, CA, United States,
3
Rhythmia
Medical-Boston Scientific, Inc., MA, United States,
4
Institute
for Advanced Studies, Lucca, Italy,
5
Heart
Rhythm Institute, OK, United States
Myocardial infarction can lead to chronic iron
deposition that can be accurately quantified with T2*
MRI. However, its long-term fate and influence on
myocardial electrical properties remain largely
unexplored. In this study we used T2* MRI to
characterize chronic iron deposition in canines with
chronic myocardial infarction in combination with
impedance spectroscopy, surface ECG indices and
electroanatomical maps to demonstrate that the
electrical behavior of infarcted hearts with iron appear
to be different from those without iron.
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